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Old 12-24-2010, 04:51 PM   #1
The Bug Whisperer
 
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Default Humans as a Microbial Community

Recent genomic studies indicate that some 90 percent of the cells found in the average human are microbial (Human Microbiome Project - Overview). Obviously, this indicates somewhat of an intimate relationship. Now it appears that our microbial companions can have a very profound effect on our innermost workings - from SCIENCE, Volume 330, Issue 6012 (December 24 2010) -
"Efforts to sequence the human microbiome—the genomes of all the microbes that inhabit our bodies—have demonstrated its enormous diversity. Analyses to probe the various functions of the microbiota, particularly of those that reside in the gut, have revealed that our microbiota has a profound impact on the development and function of our immune systems. Lee and Mazmanian (p. 1768) review how the microbiota influences the development of the adaptive immune system. Specific species and families of microbiota support the differentiation of particular populations of T cells, and alterations in intestinal microbiota affect the development of inflammation and autoimmunity."

This nugget led me to do a little searching, which found an interesting sounding book: GI Microbiota and Regulation of the Immune System - see GI Microbiota and Regulation of the Immune System

Defining a human being becomes ever more interesting...
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Old 12-24-2010, 05:13 PM   #2
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90%??!! Wow.
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autoimmune, autoimmunity, cells, community, genomic, genomic studies, gi tract, history, human, human health, humans, immune system, inflammation, intestinal microbiota, microbial, microbial companions, microbiota, natural, natural history, probiotics, research, studies

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